Covid-19 vaccine thread

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The Trump administration has been somewhat reluctant to use the Defense Production Act, a law that allows the federal government to order private industries to initiate or prioritize certain orders.

But Celine Gounder, a member of Biden’s COVID-19 Advisory Board, said Monday that Biden’s DPA use would mark a departure from the current President.
 

Innula Zenovka

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How effective is the Oxford vaccine?

There are three figures doing the rounds - 62%, 70% and 90%.

The first analysis of the trial data showed 70% of people were protected from developing Covid-19 and nobody developed severe disease or needed hospital treatment.

The figure was just 62% when people were given two full doses of the jab and 90% when they were first given a half dose and then a full one.

The Medicines and Healthcare products Regulatory Agency (MHRA) has approved two full doses of the Oxford-AstraZeneca vaccine.

However, unpublished data suggests that leaving a longer gap between the first and second doses increases the overall effectiveness of the jab.

There was not enough clear data to approve the half-dose, full-dose idea.

All the vaccines are expected to be equally effective against the new variants of the virus that have emerged.
 

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Aurora Medical Center first reported on the spoiled doses on Saturday, and said they had been accidentally left out overnight by an employee at Aurora Medical Center in Grafton.

In a statement late Wednesday, Aurora said the employee involved “today acknowledged that they intentionally removed the vaccine from refrigeration.”

Aurora's statement said they had fired the employee and referred the matter to authorities for further investigation. Their statement said nothing about a possible motive for the action, and health system officials didn't immediately respond to messages seeking more information.
And 500 doses down the drain.
 

Jolene Benoir

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Innula Zenovka

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Someone should educate Kushner all about that because from what we have seen of him over the last year, he clearly does not practice such beliefs.
From what we've seen over the last few years, Kushner, like Trump himself and all other members of his close circle of family and courtiers, has scant regard for the laws of either God or man, though, or at least not when they prove temporarily inconvenient, so I don't know that would do much good.
 

Innula Zenovka

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This is interesting, at the end of the FAQ after an article about the UK's vaccine strategy:

What does all this mean for social distancing?
At some point enough vulnerable people will have been vaccinated for cases to fall to the point where there is no danger of the NHS being overwhelmed even if rules are eased. How many is the most pressing question of the new year.
That is, if I properly understand it, the absolute priority is to save patients' lives. This includes the lives of patients saved by preventing the NHS being overwhelmed by COVID patients, thus denying some patients necessary lifesaving treatment, whether for COVID-19 or something else.

Therefore, it follows that vaccinations should be offered to patients on the basis not of the risk that they will contract COVID-19 but of the risk that, should they become infected, they'll become so ill that, at least, they'll have to be treated in hospital and that there's a very real danger they'll die.

So while someone in their sixties, retired, and living in a tight family bubble or along, is probably far less likely to become infected with the virus than is an emergency nurse in her 30s, with young kids living at home. However, the older people, should they catch the virus, are so much more likely to become so ill htey end up in hospital than the nurse who is half their age, thus both risking their lives and also putting the hospitals under increasing strain.

Makes sense, I guess.

The same thinking seems to inform the contentious decision to increase the number of people who are vaccinated using the Pfizer vaccine by leaving longer than recommended between doses, which may apparently affect how long people remain immune after they first develop immunity, since at present they're more concerned about the number of people they can protect right now than they are about how long the protection lasts, because right now is when we need the hospital beds (or three weeks after the vaccination) and we can worry about the beds we need in March or April a bit nearer the time.



Evernote link because paywall
 
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Bartholomew Gallacher

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Bert Hubert, the Dutch guy which founded PowerDNS, has a very interesting read about reverse engineering the Biontech vaccine based on the publication of the whole vaccine construction code by the WHO. According to Hubert they used some really clever tricks to make that vaccine working as intended.

 

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I'm not sure what the motives of that pharmacist were, except to try to discredit the effectiveness of the vaccine for some reason.
 
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Chalice Yao

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Bert Hubert, the Dutch guy which founded PowerDNS, has a very interesting read about reverse engineering the Biontech vaccine based on the publication of the whole vaccine construction code by the WHO. According to Hubert they used some really clever tricks to make that vaccine working as intended.

Oh man, I absolutely *LOVE* this article. It wonderfully explains how the vaccine is pretty much a programmed executable for our cells to run and print proteins with, and what each piece of the vaccine-code does, and why.

Most informative article I read in 2021, 11/10.
 

Sid

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That stuff goes way above my head.
So the only things I'm interested in are that it works as advertised and that it will be available in larger quantities soon.
 

Innula Zenovka

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That stuff goes way above my head.
So the only things I'm interested in are that it works as advertised and that it will be available in larger quantities soon.
Much of it was beyond me, too, but the little bits that I could follow were interesting in themselves.
 

Innula Zenovka

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The policy seems to be that it's certainly not recommended, but it is permissible in certain situations, where the it's not reasonably possible to offer the a booster of the original vaccine (one of the examples I've read is when there's no reasonable expectation that, if offered another appointment when the original vaccine is available, the patient will, in fact, attend).

ETA: Thread and comments

 
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