Covid-19 vaccine thread

[Soen Eber]

The reverse-engineering is very clever, at least as I understand it and as described. So what it does is:

1) Trick the immune system to not attack the vaccine by modding one of the nucleotides. This trick cannot be performed "in the wild".

2) Instruct the ribosome to make COVID-19 spike proteins. The modified necleotides are still recognized as the unmodified necleotides (apparently the ribosome is using legacy code while the immune system has all the latest patches).

3) Trick the ribosome into thinking the vaccine is coming from the nucleus and therefore is not foreign.

4) Metadata spurs the ribosome to create many copies of the spike protein immediately.

5) The vaccine "address label" pushes the spike proteins out of the cell.

6) Use known hacks to:
a) optimize the production of the spike proteins
b) fold the spike proteins to mimic the virus spike

7) Send a "stop" code to mark the end of the spike protein transcription.

8) Set an optimized "Time to Live" protein sequence so the spike proteins don't get "garbage collected".

The end result is the freely circulating spike proteins train the immune system.

I have two takeaways: a) Damn, humans are clever! and b) the ease of weaponization of this technology is going to give me nightmares.

 

[Arkady Arkright]

England health officials defend contingency plan to mix Covid vaccines

PHE says it is reasonable to mix the two approved vaccines in exceptional circumstances

www.theguardian.com

The policy seems to be that it's certainly not recommended, but it is permissible in certain situations, where the it's not reasonably possible to offer the a booster of the original vaccine (one of the examples I've read is when there's no reasonable expectation that, if offered another appointment when the original vaccine is available, the patient will, in fact, attend).

The way I read that is that PHE are recommending actions that are completely untested, on an assumption about the way the different vaccines interact with each other, in order to cover their own (and politicians) arses about slow delivery. Am I being unduly cynical again ?

eta: It would appear that the original article was incorrect, see my post below.

 

[Sid]

That there would be slow limited delivery was totally clear from the beginning. The whole world wants its share, and there is only one producer that has clearance for its product, and a second one is very close to the finish line. That is never enough for a swift and broad role out of a vaccination programm.

The enormous pressure on the healthcare system and the economy are the main problems I guess.
I find it totally irresponsible behavior.

 

[Arkady Arkright]

It would appear that the NYT article was not true, my apologies to PHE - Coronavirus: BMJ urges NYT to correct vaccine 'mixing' article Published 10 hours ago.

 

[Luisa Land]

That there would be slow limited delivery was totally clear from the beginning. The whole world wants its share, and there is only one producer that has clearance for its product, and a second one is very close to the finish line. That is never enough for a swift and broad role out of a vaccination programm.

The enormous pressure on the healthcare system and the economy are the main problems I guess.
I find it totally irresponsible behavior.

Overall, it is certainly true that there is too little vaccine available, especially now at the beginning. And it is certainly the main reason why vaccination coverage is so slow.

However, I have the impression that this argument is also used to cover up other organisational difficulties.
I only know more about Germany and the Netherlands.
Here in Germany, Biontech has delivered 1.2 million by 31 December 2020. However, the statistics only show 188,000 vaccinated people (as of 2.1.2021 8.00 a.m.).
In the Netherlands, 175,000 vaccine doses have been stored in the east of the country for some time. However, the Dutch government did not want to vaccinate the first people until 8 January and only really start the vaccination campaign on 18 January. Due to massive protests, the campaign has now been brought forward somewhat.

 

[Sid]

Starting the vaccination campaign is easy. But to continue it is a different thing.
That's why the intentional plan in NL was to start at three places in the country and then roll out more vaccination points the moment there would be a regular stream of more vaccine doses available.
But now that the pressure at the hospitals gets real high there is a change in plans and the hospitals get the available doses to start vaccinating first line medical workers first.

 

[Arkady Arkright]

The UK bureaucrats have really got their teeth into the vaccination programme, no wonder it's so slow...
Ministers urged to strip away red tape to hit UK vaccine rollout target

Some of these bureaucratic demands are ridiculous, such as the requirement to be certified in fire safety, or preventing radicalisation. There are people who have experience of giving a jab and dealing with anaphylaxis if someone had an allergic reaction, so you don’t need to see their O-level certificates or many of the other bits of paperwork they are being asked for.

 

[Luisa Land]

Starting the vaccination campaign is easy. But to continue it is a different thing.
That's why the intentional plan in NL was to start at three places in the country and then roll out more vaccination points the moment there would be a regular stream of more vaccine doses available.
But now that the pressure at the hospitals gets real high there is a change in plans and the hospitals get the available doses to start vaccinating first line medical workers first.

I don't understand...what you mean with "Starting the vaccination campaign is easy. But to continue it is a different thing."
There are currently 1 million unvaccinated doses here. As of today. The next delivery of vaccine is announced here for 8 January. That is 5 days. 200,000 doses could be vaccinated per day until the next delivery arrives.
To vaccinate such a daily ration of 200,000 has taken 6 to 7 days since the start of vaccination. At this rate, there will still be about 700,000 unvaccinated doses at the time of the next delivery.

And even if there were no vaccine to inject for a few days: isn't it better that the 150,000 (or however many) who have received a first vaccination by then have some protection, even if not complete, than that no one has been vaccinated by then?

I think the whole thing is a complex challenge and different countries around the world are taking different approaches to dealing with it. I often read the term "vaccination chaos" in connection with the USA - I can't judge that. It is important that there is enough vaccine available. But that is not the only factor that determines how well or poorly this challenge is met.and which vaccination strategy achieves the best possible effect.

 

[Sovereignty]

A thread giving good reasons not to delay second doses of vaccines.

 

[Bartholomew Gallacher]

That there would be slow limited delivery was totally clear from the beginning. The whole world wants its share, and there is only one producer that has clearance for its product, and a second one is very close to the finish line. That is never enough for a swift and broad role out of a vaccination programm.

The emergency laws of many countries world wide do contain a paragraph, which in case of a national catastrophe/emergency allow the state to circumvent copyright protection and start the production of the stuff on its own or hand it also over to other companies.

Something which most Western states didn't do - yet. France is heavily thinking about it.

The problem though is that of course there are globally not many companies around which already had before the pandemic crisis the capacity at their hand to produce billions of doses of this vaccine fast. And building new factories takes quite obviously time.

 

[Innula Zenovka]

The emergency laws of many countries world wide do contain a paragraph, which in case of a national catastrophe/emergency allow the state to circumvent copyright protection and start the production of the stuff on its own or hand it also over to other companies.

Something which most Western states didn't do - yet. France is heavily thinking about it.

The problem though is that of course there are globally not many companies around which already had before the pandemic crisis the capacity at their hand to produce billions of doses of this vaccine fast. And building new factories takes quite obviously time.

And the facilities to bottle it, including the phails, which have to be specially manufactured.

 

[Arkady Arkright]

A thread giving good reasons not to delay second doses of vaccines.

I suppose the trade off is -
a) the number who die because their second dose was delayed (with the possibility of a new mutation),
..versus..
b) how many of the unvaccinated 50% die because they didn't get a first dose (which was reserved as a second dose for someone else).

Not a calculation I'd want to be responsible for...

 

[Kamilah Hauptmann]

And the facilities to bottle it, including the phails, which have to be specially manufactured.

Why don't they use the chemtrail jets tho?

 

[Soen Eber]

Has anyone written yet if there will be a delay because of the changeover of administrations?

 

[Innula Zenovka]

Why don't they use the chemtrail jets tho?

Messes up the 5G signals and fries the chips.

 

[Essence Lumin]

Messes up the 5G signals and fries the chips.

TIL.

 

[Innula Zenovka]

 

[Katheryne Helendale]

Oh, I wish we could get rid of this damned pandemic so that restaurants can open back up. There's a place here that makes awesome fish-and-chips that I want to try again!

 

[Kamilah Hauptmann]

Oh, I wish we could get rid of this damned pandemic so that restaurants can open back up. There's a place here that makes awesome fish-and-chips that I want to try again!

Wat, no take out?

Fish and chips places here are making bank hand over fist from take out.

 

[Katheryne Helendale]

Wat, no take out?

Fish and chips places here are making bank hand over fist from take out.

I actually hadn't thought to see if they do take out. Of course, the only real problem with take-out, especially with fried foods, is that it's usually cold and nasty by the time I get it home to eat it.