Coronavirus Updates

Kalel

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we're number one! we're number one!

more then 15K cases and trump seen with an actual mask on!

:: goes and hides in his room and doesn't come out::

 

Archer

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One of the main issues with COVID-19 is how much we DON'T know about it. The greatest disservice done to people is initially describing it as "flu-like symptoms". That is like comparing a fender bender to a 60 mph head on collision both as crashes. The scope is entirely different. Not only are the long term effects unknown (we're barely at the 6 month mark), but we aren't even able to reliably detect it to know who is spreading it where. This virus is a nightmare, and until the vast majority of folks realize that they need to do whatever they can to avoid getting it and spreading it, we are going to continue to try to battle it. And the horror stories will continue to pile up.
 

Sid

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One of the main issues with COVID-19 is how much we DON'T know about it. The greatest disservice done to people is initially describing it as "flu-like symptoms". That is like comparing a fender bender to a 60 mph head on collision both as crashes. The scope is entirely different. Not only are the long term effects unknown (we're barely at the 6 month mark), but we aren't even able to reliably detect it to know who is spreading it where. This virus is a nightmare, and until the vast majority of folks realize that they need to do whatever they can to avoid getting it and spreading it, we are going to continue to try to battle it. And the horror stories will continue to pile up.
As our PM put it yesterday in an interview:
We have to take decisions with less than 50% of the needed information available.
 

Kalel

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One of the main issues with COVID-19 is how much we DON'T know about it. The greatest disservice done to people is initially describing it as "flu-like symptoms". That is like comparing a fender bender to a 60 mph head on collision both as crashes. The scope is entirely different. Not only are the long term effects unknown (we're barely at the 6 month mark), but we aren't even able to reliably detect it to know who is spreading it where. This virus is a nightmare, and until the vast majority of folks realize that they need to do whatever they can to avoid getting it and spreading it, we are going to continue to try to battle it. And the horror stories will continue to pile up.
there have been alot of pop up articles recently of residual damage.. Even people who show no symptoms have lung damage. Autopises coming back with blood clots and other things that could change someone life forever even if they did survive. some people think Death is worst thing to happen to someone. they haven't felt what it's like to suffer with a consistant like symptoms for the rest of your life...


 

GoblinCampFollower

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You mistook my reply for misandry. I'm a misanthrope. Male infertility is just a means to an end: fewer people.
LOL, I completely understood you and agree. I was just cracking the obvious joke. And my second comment was referencing the fact that fewer people was better for the climate...

Why are you against the idea of sex without the repercussions of conception? :hellokitty:
oh, I'm not! haha. Though I also wonder if impotence and not just infertility could be affected by those factors... but we'll see!
 

Sovereignty

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Seheult's latest video discusses two post-mortem studies focusing on thrombosis. Some images not for the squeamish. He's really talking to a medical audience with this video, but it's still interesting.

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series

Some things that might stand out to a lay person like me:
  • Some of these patients were getting full anti-coagulant treatment and still had lots of blood clots. Seheult commented he's seen this happen in his own practice. He thinks patients are showing up at the hospital already suffering from coagulopathy.
  • There were lots of megakaryocytes found in places they shouldn't be so many. These are cells that originate in bone marrow and create blood platelets. This was quite a mystery to Seheult. There also were excess megakaryocytes in the bone marrow.
  • According to Seheult, the findings did not obviously support Seheult's hypothesis about what promotes clotting, but did not rule it out either. The article states: "The mechanism for this prothrombotic milieu is yet to be determined."
Prognostic factors associated with mortality risk and disease progression in 639 critically ill patients with COVID-19 in Europe: Initial report of the international RISC-19-ICU prospective observational cohort

These prognostic factors are not the familar co-morbidities. They are mostlly measurements from blood work. There is one based on oxygen supplementation compared to oxygen levels in the blood.

Seheult proposes that all of the listed factors can be related to coagulopathy even though they were found, statistically, to be independent. Seheult suggests that some of the independence can be explained by where micro-thrombi occur, e.g., the kidneys versus the lungs. The independence of the factors may also be related to the presence of distinct comorbidities. He points out that the one factor that best distinguishes between survival and non-survival is the one most directly related to the presence of coagulation, d-dimer.
 
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Sovereignty

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From the original paper:
This study found that in patients who had recovered from COVID-19, 87.4% reported persistence of at least 1 symptom, particularly fatigue and dyspnea. Limitations of the study include the lack of information on symptom history before acute COVID-19 illness and the lack of details on symptom severity. Furthermore, this is a single-center study with a relatively small number of patients and without a control group of patients discharged for other reasons. Patients with community-acquired pneumonia can also have persistent symptoms, suggesting that these findings may not be exclusive to COVID-19.
If blood vessels around their lungs contain blood clots, I'm not surprised.
 
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Sovereignty

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Spoke with @vicderbyshire this morning, highlighting the debilitating symptoms related to #LongCovid. Grateful to all media that are now picking this up, hopefully it will send a message to Government that we need immediate action.
What would the immediate action be? What priority should it be given?

As long as the particular actions needed are vague, their priority will necessarily remain low.
 

Innula Zenovka

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What would the immediate action be? What priority should it be given?

As long as the particular actions needed are vague, their priority will necessarily remain low.
As I understand it, the main concerns are for regular monitoring to be offered, at least, by patients' GPs (family doctors) and by hospital units as necessary.

I think people also want it officially recognised for employment purposes and for unemployment and disability benefits that people may not be able to return to work for some time after being pronounced clear of the virus, and that they may be left with permanent disabilities.
 

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In this issue of JAMA, Wang et al present evidence that universal masking of health care workers (HCWs) and patients can help reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections.1 In the largest health care system in Massachusetts with more than 75 000 employees, in tandem with routine symptom screening and diagnostic testing of symptomatic HCWs for SARS-CoV-2 infection, leadership mandated a policy of universal masking for all HCWs as well as for all patients. The authors present data that prior to implementation of universal masking in late March 2020, new infections among HCWs with direct or indirect patient contact were increasing exponentially, from 0% to 21.3% (a mean increase of 1.16% per day). However, after the universal masking policy was in place, the proportion of symptomatic HCWs with positive test results steadily declined, from 14.7% to 11.5% (a mean decrease of 0.49% per day). Although not a randomized clinical trial, this study provides critically important data to emphasize that masking helps prevent transmission of SARS-CoV-2.
tl;dr summary: WEAR A FUCKING MASK.