Creme Puff's owner, Jake Perry, said her diet consisted of dry cat food supplemented with broccoli, eggs, turkey bacon, coffee with cream, and—every two days—"an eyedropper full of red wine". Perry claimed that this diet was key to her longevity, and that the wine "circulated the arteries".
Perry also kept Creme Puff very active within the home, turning his garage into a movie theater that played nature documentaries for his cats. Wooden steps were built into the walls of Perry's home for the cats to climb on, and Perry had built a screened enclosure in his backyard for his pets, including Creme Puff, to enjoy the outdoors